3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE

3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE - Names and Identifiers

Name	3-fluoro-4-(trifluoromethyl)benzoyl chloride
Synonyms	à,à,à,4-tetrafluoro-p-toluoyl chloride 3-Fluoro-4-(trifluoroMe)benzoyl chloride 3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE 3-fluoro-4-(trifluoromethyl)benzoyl chloride alpha,alpha,alpha,4-Tetrafluoro-p-toluoyl chloride 4-(Chlorocarbonyl)-2-fluorobenzotrifluoride, 4-(Chlorocarbonyl)-alpha,alpha,alpha,2-tetrafluorotoluene
CAS	216144-68-2
EINECS	623-664-9
InChI	InChI=1/C8H3ClF4O/c9-7(14)4-1-2-5(6(10)3-4)8(11,12)13/h1-3H

3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE - Physico-chemical Properties

Molecular Formula	C8H3ClF4O
Molar Mass	226.56
Density	1.486 g/mL at 25 °C (lit.)
Boling Point	152 °C (lit.)
Flash Point	179°F
Water Solubility	Not miscible or difficult to mix in water.
Vapor Presure	0.132mmHg at 25°C
Storage Condition	Inert atmosphere,Room Temperature
Sensitive	Moisture Sensitive
Refractive Index	n20/D 1.465(lit.)
MDL	MFCD00236284

3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	34 - Causes burns
Safety Description	S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	UN 3265 8/PG 2
WGK Germany	3
HS Code	29163990
Hazard Note	Corrosive
Hazard Class	8
Packing Group	II

3-FLUORO-4-(TRIFLUOROMETHYL)BENZOYL CHLORIDE - Introduction

3-fluoro-4-(trifluoromethyl)benzoyl chloride is an organic compound with the chemical formula C8H3ClF4O. It is a colorless to pale yellow liquid with a pungent odor.

Its main use is as an important chemical synthesis intermediate. It can be used to synthesize organic compounds with special structures and functions. Especially in the fields of medicine, pesticide and material science, it is often used in synthetic drugs, dyes, pesticides and high-performance materials.

There are two main methods for the preparation of 3-fluoro-4-(trifluoromethyl)benzoyl chloride. One is obtained by chlorination of 3-fluoro -4-(trifluoromethyl) benzoic acid. Another method is obtained by reacting 3-fluoro-4-(trifluoromethyl) benzyl alcohol with thionyl chloride. These preparation methods need to be carried out under cooling conditions and sufficient ventilation conditions, and attention should be paid to the safety of operation.

When using 3-fluoro-4-(trifluoromethyl)benzoyl chloride, you need to pay attention to its irritation and corrosiveness. Contact with skin, eyes and respiratory tract should be avoided. Wear appropriate protective equipment, such as lab gloves, goggles, and respiratory protection. At the same time, storage and handling to avoid contact with organic matter, oxidants and strong alkali, so as not to cause dangerous reactions. In the event of an accident such as inhalation, contact or ingestion, seek medical help immediately and show the product label or safety data sheet to the doctor.

Last Update：2024-04-09 21:11:58